Biochimica et biophysica acta. Proteins and proteomicsGlycine HydroxymethyltransferaseEscherichia coliHumansSerineSubstrate Specificity
Multifunctionality analysis of serine hydroxymethyltransferases from human and Escherichia coli.
Mahiro Hayashi, Kumiko Sakai-Kato, Tetsuya Miyamoto
Published: 202610.1016/j.bbapap.2025.141107
Abstract
Serine hydroxymethyltransferase (SHMT) catalyzes the conversion of l-serine and tetrahydrofolate (THF) to glycine and 5,10-methylenetetrahydrofolate, respectively. In a previous study, we found that human and Escherichia coli SHMTs possess THF-depend…
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