Biochimica et biophysica acta. BiomembranesKCNQ1 Potassium ChannelHumansMembrane ProteinsHEK293 CellsAnimals
Transmembrane channel-like 4 (TMC4) could act as a negative regulator of KCNQ1 (Kv7.1) potassium channel.
Hirota Aoyagi, Koya Kawaguchi, Saori Yano-Nashimoto, Soichiro Yamaguchi
Published: 202610.1016/j.bbamem.2025.184460
Abstract
TMC4 is a member of the transmembrane channel-like (TMC) protein family. In this family, TMC1 and TMC2 are thought to form the mechano-electrical transduction (MET) channel in the inner ear. On the other hand, the intrinsic functions of the other TMC…
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