Biochimica et biophysica acta. Molecular cell research
USP49 regulates lipid metabolism in hepatocellular carcinoma by stabilizing RACK1 to promote tumor proliferation and migration.
Weikang Xu, Jijun Shan, Jifei Wang, Yudi Zhou, Yiming Ouyang, Yananlan Chen, Qiyang Zhou
Published: 202610.1016/j.bbamcr.2026.120107
Abstract
Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options. While ubiquitin-specific peptidase 49 (USP49) has been implicated in various cancers, its role in HCC is unclear. Here, we found that USP49 is upregulated in…
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