Biochimica et biophysica acta. Molecular cell researchAnimalsCell ProliferationMuscleSmoothVascular
Ephrin-A1/EphA2 modulates vascular smooth muscle cell proliferation in vitro, while VSMC-specific ephrin-A1 deletion is not sufficient to alter arteriosclerosis in vivo.
Antje Augstein, Sebastian Porth, Johannes Mierke, Janet Friedrich, Stefanie Jellinghaus, Axel Linke, Volker Adams, David M Poitz
Published: 202610.1016/j.bbamcr.2025.120098
Abstract
Atherosclerosis, the leading cause of heart attack and stroke, involves plaque formation driven by various cell types, including endothelial cells, immune cells and vascular smooth muscle cells (VSMCs). VSMCs undergo a phenotypic switch from a contra…
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