Biochimica et biophysica acta. Molecular cell researchAnimalsCell DifferentiationMiceCachexiaCell Line
Assessing the involvement of tumor-secreted factors in the inhibition of muscle differentiation.
Miranda van der Ende, Xiaolin Li, Mieke Poland, Fleur Jansen, Jocelijn Meijerink, Jaap Keijer, Renger F Witkamp, Sander Grefte, Klaske van Norren
Published: 202610.1016/j.bbamcr.2025.120093
Abstract
Cancer cachexia is a multifactorial syndrome characterized by involuntary and pathological weight loss, predominantly caused by muscle wasting. While tumors can elicit detrimental effects on skeletal muscle function, the contribution of specific tumo…
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