Biochimica et biophysica acta. Molecular cell researchAnimalsMicroRNAsMiceTransgenicMuscle
Transgenic overexpression of miR-486 and sAnk1.5 does not alter glucose handling in mice.
S Buonocore, F Fiore, E M Rubino, M R Catallo, L Raucci, A Laurino, D Rossi, E Pierantozzi, V Sorrentino
Published: 202610.1016/j.bbamcr.2025.120087
Abstract
Recent studies have shown that the C allele of SNP rs508419 is associated with susceptibility to Type 2 diabetes (T2D). This SNP lies within the muscle-specific P2 promoter of human ANK1, which drives transcription of the sAnk1.5 isoform and miR-486.…
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