Biochimica et biophysica acta. Molecular cell researchAnimalsMitochondriaMacrophagesMiceColitis
Loss of Sugen Kinase 495 in macrophages alleviates chronic colitis by improving mitochondrial stress.
Jikai He, Yuanmei Lou, Pingan Yao, Shiguang Yang, Jinliang Dong, Qifeng Yu
Published: 202610.1016/j.bbamcr.2025.120072
Abstract
Inflammatory bowel disease (IBD), highlighted by chronic intestinal inflammation, is an escalating global health concern. The pathogenesis of IBD is not fully understood, with DSS-induced chronic colitis in mice serving as a prevalent model, characte…
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