Biochimica et biophysica acta. Molecular and cell biology of lipidsAnimalsHepatic Stellate CellsDietHigh-FatMice
Curcumol ameliorates high-fat diet-induced hepatic fibrosis via dual regulation of FXR-CREB and Rab18-mediated hepatic stellate cell lipophagy.
Na Wei, Wanyu Feng, Meijun Pan, Xinyi Xu, Shuguo Zheng, Huanhuan Jin
Published: 202610.1016/j.bbalip.2025.159710
Abstract
Curcumol, a bioactive constituent derived from Rhizoma Curcumae roots, possesses anti-inflammatory and anti-viral properties. This study investigated its therapeutic effects on lipophagy in hepatic stellate cells (HSCs) and lipid accumulation in hepa…
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