Biochimica et biophysica acta. Molecular and cell biology of lipidsATP Binding Cassette Transporter 1AnimalsTRPV Cation ChannelsLipoproteinsLDL
Melatonin ameliorates ox-LDL-induced lipid accumulation and enhances ABCA1 expression in VSMCs via inhibition of the TRPV1-Ca2+-calpain signaling pathway.
Yuehong Tang, Yujiao Peng, Yaling Zhang, Wenjuan Tong, Shaowei Sun
Published: 202610.1016/j.bbalip.2025.159704
Abstract
Oxidized low-density lipoprotein (ox-LDL) has been shown to induce significant lipid accumulation and disrupt cholesterol homeostasis in vascular smooth muscle cells (VSMCs), which may contribute to the development of atherosclerosis (AS). In this st…
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