Biochimica et biophysica acta. Gene regulatory mechanisms
Tet2-mediated Pref-1 activation delays adipocyte differentiation.
Brigitta Veda Devani, Hye Su Moon, Ana Braza, Timoty Ekaputra, Audrey Christine, Jae Won Shim, Su Jung Song
Published: 202610.1016/j.bbagrm.2026.195137
Abstract
Ten-eleven translocation 2 (Tet2) catalyzes the conversion of 5-methylcytosine to 5-hydroxymethylcytosine, facilitating active DNA demethylation. Although implicated in adipogenesis, its precise role remains controversial. Here, we investigated Tet2…
Preview only. Read the full abstract at the source