Biochimica et biophysica acta. Gene regulatory mechanismsHumansTranscription Factor RelAGene Expression RegulationNeoplasticCarcinogenesis
Identification of a novel p65-p68 loop: A crucial determinant for p68 gene regulation in oncogenesis.
Mrinal K Ghosh, Sunny Kumar, Veenita Khare, Siddik Sarkar, Shaheda Tabassum, Malini Basu
Published: 202510.1016/j.bbagrm.2025.195120
Abstract
DEAD-box RNA helicase DDX5 (p68), located on chromosome 17, specifically at the 17q23.3 region), is overexpressed in most of the cancers, including colorectal cancer (CRC) and glioma, thereby gaining prominence as a potential biomarker. There is a pa…
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