Biochimica et biophysica acta. General subjectsAnimalsMitophagyMiceSpermidineSalivary Glands
Spermidine deficiency induces BNIP3/LC3B-mediated mitophagy in the salivary glands of accelerated aging mice.
Nguyen Khanh Toan, Manh Dat Duong, Nguyen Duy Phu, Le Viet Thanh, Sang-Gun Ahn
Published: 202610.1016/j.bbagen.2025.130897
Abstract
Aging is associated with mitochondrial dysfunction and altered autophagic processes, particularly in secretory organs such as the salivary glands. In this study, we investigated metabolic changes and their interactions with mitophagy in primary saliv…
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