Biochimica et biophysica acta. General subjectsAquaporin 4LipoylationHumansProtein IsoformsLipid Bilayers
Size of aquaporin-4 orthogonal arrays of particles are affected by the palmitoylation state of the M1 isoform.
Jessica D Carder, Barbara Barile, Alessia Memeo, Eric P Jacobo, Grazia Paola Nicchia, James A Brozik
Published: 202510.1016/j.bbagen.2025.130866
Abstract
Human aquaporin-4 (AQP4) is a water-channel protein crucial for water-ion homeostasis in the central nervous system. Dysregulation of AQP4 function is linked to neurological conditions like brain edema, neuromyelitis optica, and epilepsy. AQP4 has tw…
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