Biochimica et biophysica acta. Molecular basis of disease
Targeting the NLRP3 inflammasome signalling in acute myeloid leukemia: Mechanisms, therapeutics, and future directions.
Sally H Fayad, Alaa Mohamed Salah, Ayad A Jaffa, Nadine Darwiche
Published: 202510.1016/j.bbadis.2025.168143
Abstract
Acute myeloid leukemia (AML) is one of the most frequent hematological malignancies. It is a complex and aggressive disease of undifferentiated hematopoietic progenitor cells, with high rates of relapse and drug resistance, posing significant clinica…
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