Biochimica et biophysica acta. Molecular basis of disease
INSR/AKT1 axis promotes cells proliferation and migration in acute myeloid leukemia.
Liman Lin, Chunle Zhao, Xiaoya Cai, Aiguo Liu, Min Xiao, Liting Chen, Dengju Li
Published: 202510.1016/j.bbadis.2025.168132
Abstract
Chemotherapy resistance represents a major challenge in relapsed and refractory acute myeloid leukemia (AML). Therefore, it is necessary to investigate the mechanisms underlying chemotherapy resistance in AML. INSR not only highly expressed in AML ce…
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