Biochimica et biophysica acta. Molecular basis of disease
Vitexin targets USP49-GRPR deubiquitination axis in medullary thyroid carcinoma therapy.
Qing Xia, Shuai Dong, Wenjun Xu, Qinmei Lai, Hanlin Song, Wei Zhang
Published: 202510.1016/j.bbadis.2025.168128
Abstract
Medullary thyroid carcinoma (MTC) is a rare, aggressive neuroendocrine malignancy with limited therapeutic options, often exhibiting resistance to targeted therapies. This study demonstrates that the natural flavonoid vitexin suppresses MTC progressi…
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