Biochimica et biophysica acta. Molecular basis of diseaseHumansIdiopathic Pulmonary FibrosisMachine LearningComputational BiologyGene Regulatory Networks
Integrated bioinformatics and machine learning analysis identify CROT as a regulator of immunological features in idiopathic pulmonary fibrosis.
Tingting Song, Mengfan Bu, Qianling Song, Beibei Zhan, Wenning Liu, Mengxin Hu, Guangcui Xu, Zijiang Yang, Keda Zhao, Yichun Bai, Sanqiao Yao, Yingzheng Zhao
Published: 202610.1016/j.bbadis.2025.168100
Abstract
Mitochondrial dysfunction and immune dysregulation contribute to the pathogenesis of idiopathic pulmonary fibrosis (IPF). This study systematically identifies mitochondrial-related core regulatory genes and elucidates their potential associations wit…
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