Autonomic neuroscience : basic & clinicalAnimalsBaroreflexRatsInbred WKYMale
Vericiguat attenuates the dynamic gain of open-loop baroreflex function in a low-frequency range.
Aimi Yokoi, Toru Kawada, Nana Hiraki, Midori Kakuuchi, Takuya Nishikawa, Masafumi Fukumitsu, Kei Sato, Joe Alexander, Ryou Tanaka, Keita Saku
Published: 202510.1016/j.autneu.2025.103354
Abstract
Vericiguat, a soluble guanylate cyclase stimulator, enhances the production of cyclic guanosine monophosphate through nitric oxide (NO)-dependent and -independent mechanisms. We examined the effects of vericiguat on the open-loop dynamic characterist…
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