Physiologic and clinical sequelae after pneumatic tourniquet release in frail patients undergoing total knee arthroplasty under regional anesthesia: a prospective observational study.

BACKGROUND: Tourniquet deflation during total knee arthroplasty (TKA) produces abrupt reperfusion physiology, including hyperkalemia, acidosis, and hemodynamic instability. Frail patients are particularly vulnerable; however, this population has not…

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