Ageing research reviewsPyroptosisHumansFerroptosisNucleotidyltransferasesHeart Failure
Ferroptosis and pyroptosis: Mediating mechanisms of the cGAS/STING pathway and therapeutic strategies in heart failure.
Zeyu Zhang, Zhihua Yang, Shuai Wang, Xianliang Wang, Jingyuan Mao
Published: 202610.1016/j.arr.2025.102932
Abstract
Focusing on cardiomyocyte survival in the prevention and treatment of heart failure, ferroptosis and pyroptosis-two vital modes of cell death-have attracted intense interest. The immunomodulatory cGAS/STING axis, a currently prominent pathway, has al…
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