Redox-sensitive high mobility group box 1 (HMGB1) is a multifunctional regulator of cellular senescence, inflammation, and immunosuppression: Impact on the aging process.

Aging is a multifaceted process involving cellular senescence and a significant remodeling of the immune network driven by the senescence-associated secretory phenotype (SASP). This progressive process needs adaptable drivers to push it forward. The…

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