Annals of the rheumatic diseases
Antimitochondrial antibodies in systemic lupus erythematosus are associated with and predict nephritis, arterial vascular events, and mortality.
Yann L C Becker, Éric Boilard, Emmanuelle Rollet-Labelle, Christian Lood, Anne-Sophie Julien, Michal Abrahamowicz, Isabelle Allaeys, May Choi, Joannie Leclerc, Tania Lévesque, Murray Urowitz, John G Hanly, Caroline Gordon, Sang-Cheol Bae, Juanita Romero-Diaz
Published: 202510.1016/j.ard.2025.11.007
Abstract
OBJECTIVES: Systemic lupus erythematosus (SLE) remains a deadly disease, yet our ability to predict adverse outcomes is poor. Mitochondria are organelles recognised by the immune system when released from cells, and antimitochondrial antibodies (AMA)…
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