Archives of oral biologyPorphyromonas gingivalisFibroblastsGingivaAnimalsHumans
Ganoderic acid A attenuates Porphyromonas gingivalis-induced adhesion molecule expression in gingival fibroblasts and tissues via inhibition of NLRP6 inflammasome activation.
Yuanbo Wang, Jianru Liu, Xiangying Ouyang, Wenyi Liu, Peiying Lyu, Shengnan Zhang, Jing Guo
Published: 202610.1016/j.archoralbio.2025.106429
Abstract
OBJECTIVES: This study aimed to elucidate the regulatory effects and mechanisms of Ganoderic acid A (GAA) on Porphyromonas gingivalis (P. gingivalis)-induced expression of adhesion molecules in human gingival fibroblasts (hGFs) and periodontal tissue…
Preview only. Read the full abstract at the source