Archives of gerontology and geriatricsAnimalsMaleCellular SenescenceRatsMitochondria
Inhibition of c-Jun/Bak signaling alleviates endothelial cell senescence and inflammation caused by mitochondrial dysfunction in DMED.
Ma Jianxiong, Guo Yingxue, Zhongliao Zeng, Yuyi Li, Huang Jie, He Qiang
Published: 202610.1016/j.archger.2025.106123
Abstract
Endothelial dysfunction is a key contributor to diabetic complications, including erectile dysfunction (ED). Using single-cell RNA sequencing and transcriptomic analysis of diabetic ED (DMED), this study identifies the c-Jun/Bak pathway as a key driv…
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