Antiviral researchVirus InternalizationHemorrhagic Fever VirusCrimean-CongoHumansAntiviral Agents
Identification of claramine and anidulafungin as entry inhibitors of Crimean-Congo hemorrhagic fever virus.
Yasuteru Sakurai, Minato Hirano, Sayaka Okada, Yohei Kurosaki, Rokusuke Yoshikawa, John N Barr, Roger Hewson, Kentaro Yoshii, Jiro Yasuda
Published: 202610.1016/j.antiviral.2026.106343
Abstract
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne enveloped virus that causes a severe disease in humans. Despite its wide geographic distribution, no approved vaccines or therapeutics exist. In this study, we achieved high-titer producti…
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