Antiviral researchAntiviral AgentsPeptidomimeticsAnimalsMiceEnterovirus
An orally available peptidomimetic with broad-spectrum antiviral activity targeting the enterovirus 2C helicase.
Chang Wang, Huoyan Tong, Xi Zhou, Yuan Fang
Published: 202610.1016/j.antiviral.2025.106341
Abstract
Enteroviruses (EVs) are significant human pathogens, and the development of orally available, broad-spectrum antiviral agents remains an urgent need. The viral protein 2C, a conserved nonstructural protein with helicase activity, is a promising targe…
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