Antiviral researchVirus ReplicationHumansHepatitis B virusRNA-Binding ProteinsAdenosine
Targeted inhibition of IGF2BP1 effectively suppresses HBV replication via an m6A-dependent manner.
Deyao Li, Yuxin Song, Danjuan Lu, Yanhua Zhang, Chenxiao Qu, Guiwen Guan, Yuexi Ma, Tianhao Mao, Liwei Zheng, Yi Wang, Wenhui Song, Ting Zhang, Fengmin Lu, Jing Ning, Xiangmei Chen
Published: 202610.1016/j.antiviral.2025.106310
Abstract
Elucidation of the regulation mechanism of hepatitis B virus (HBV) replication will provide potential targets for the development of novel anti-HBV therapeutics. It has been reported that the N6-methyladenosine (m6A) modification of HBV RNA plays a c…
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