Annals of oncology : official journal of the European Society for Medical Oncology
Datopotamab deruxtecan versus chemotherapy in previously treated inoperable/metastatic hormone receptor-positive, HER2-negative breast cancer: final overall survival analysis of the phase III TROPION-Breast01 study.
B Pistilli, K Jhaveri, S-A Im, S Pernas, M De Laurentiis, S Wang, N Martínez Jañez, G Borges, D W Cescon, M Hattori, Y-S Lu, E Hamilton, J Tsurutani, K Kalinsky, P E Rubini Liedke
Published: 202510.1016/j.annonc.2025.12.017
Abstract
BACKGROUND: The TROPION-Breast01 study (NCT05104866) demonstrated statistically significant and clinically meaningful improvement in progression-free survival (PFS) by blinded independent central review (BICR) with the trophoblast cell-surface antige…
Preview only. Read the full abstract at the source