Annals of diagnostic pathologyHumansCarcinomaRenal CellKidney NeoplasmsSensitivity and Specificity
Chromosomal alterations in 7, 17, and Y demonstrate comparable sensitivity and superior specificity to diffuse strong AMACR immunostaining for papillary renal cell carcinoma.
Yang Liu, Jun Yuan, Haimin Xu, Xianwei Yang, Chaofu Wang, Luting Zhou, Xiaoqun Yang
Published: 202610.1016/j.anndiagpath.2025.152583
Abstract
The diagnostic criteria for papillary renal cell carcinoma (PRCC) include diffuse strong AMACR and retained FH expression. Although chromosomal alterations in 7/17/Y are frequent molecular findings in PRCC, they are not included in its diagnostic cri…
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