Anaerobe
Ursodeoxycholic acid inhibits biofilm formation and bacterial adhesion of Clostridioides difficile.
Xiaoxia Zhang, Min Quan, Zhiyong Zong, Xiaohui Wang
Published: 202610.1016/j.anaerobe.2026.103023
Abstract
UDCA exhibits limited direct bacteriostatic activity against Clostridioides difficile with a high MIC90 of >128 μg/mL against 121 clinical strains. However, compared with vancomycin, UDCA significantly impedes biofilm formation and bacterial adherenc…
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