American journal of surgeryHumansThyroid NoduleFemaleMiddle AgedRetrospective Studies
Diagnostic value of molecular testing for evaluating thyroid nodules greater than 4 centimeters.
Niranjna Swaminathan, ZhiXing Song, Christopher Wu, Ramsha Akhund, Jessica Fazendin, Brenessa Lindeman, Herbert Chen, Andrea Gillis
Published: 202610.1016/j.amjsurg.2025.116755
Abstract
BACKGROUND: Molecular testing (MT) aids in reducing unnecessary thyroidectomy for indeterminate thyroid nodules, primarily due to its high negative predictive value (NPV). However, its reliability in large nodules (≥4 cm), which carry a higher malig…
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