Allergology international : official journal of the Japanese Society of Allergology
5-hydroxyeicosatetraenoic acid and 12-hydroxyeicosapentaenoic acid regulate basophil and mast cell activation and basophil recruitment in chronic spontaneous urticaria.
Mana Ito, Yoshimi Miki, Shota Toyoshima, Maho Tagui, Koremasa Hayama, Hideki Fujita, Yoshitaka Taketomi, Makoto Murakami, Yoshimichi Okayama
Published: 202610.1016/j.alit.2025.12.005
Abstract
BACKGROUND: The underlying pathomechanisms of wheal reaction enlargement in chronic spontaneous urticaria (CSU) remain largely unclear. We hypothesized that the activation of mast cells (MCs) and recruitment of basophils to locally inflamed skin woul…
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