Allergology international : official journal of the Japanese Society of Allergology
The Cyto-LTT: A multiplex cytokine assay to detect and assess the strength of T cell reactivity in drug hypersensitivity.
Tim Peyer, Lester Thoo, Daniel Yerly, Oliver Hausmann, Lukas Joerg, Werner J Pichler
Published: 202510.1016/j.alit.2025.09.004
Abstract
BACKGROUND: The conventional in vitro lymphocyte transformation test (LTT) for diagnosing drug hypersensitivity reactions (DHRs) is limited by low sensitivity. To improve detection and assess T cell activation strength, we adapted this test to a cyto…
Preview only. Read the full abstract at the source