American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Tubule-Derived GDF15 Limits Renal Transplant Injury by Reprogramming Macrophage Responses.
Lang Shi, Sen Zhou, Juan Zhao, Haiqian An, Chunming Chen, Yao Xia, Ziyu Yan, Wei Li, Zhixia Song, Jiefu Zhu
Published: 202610.1016/j.ajt.2026.01.015
Abstract
Kidney transplantation remains the gold standard for end-stage renal disease, but ischemia-reperfusion injury (IRI) and delayed graft function (DGF) continue to hinder outcomes. Growth differentiation factor 15 (GDF15), a stress-responsive cytokine f…
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