American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Transmembrane protein 16F-chloride intracellular channel 1 interaction mediates recipient dendritic cell cross-decoration after transplantation.
Xiaoshi Li, Zhirong Zhang, Ying Zhang, Lei Zhang, Ai Huang, Wenlong Chen, Wenyong Zhang, Chang Li, Hongyan Wei, Cunni Zheng, Jie Liu, Quan Liu
Published: 202510.1016/j.ajt.2025.12.020
Abstract
Donor dendritic cell (DC)-derived extracellular vesicles cross-decorate recipient DCs to trigger T cell allorecognition and transplant rejection. However, the mechanism mediating recipient DC cross-decoration is unclear. Here, we find Rab27a-expressi…
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