American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Major histocompatibility complex Matchmaker: An in silico based algorithm to analyze cross-species nonhuman primate, pig, and human major histocompatibility complex compatibility at the amino acid level.
Nicolas De Bie, Joseph M Ladowski, Henry Chapman, Annette M Jackson, Bruce W Rogers
Published: 202510.1016/j.ajt.2025.10.022
Abstract
Xenotransplantation received US Food and Drug Administration approval for clinical trials in humans, and highly sensitized patients-those with antibodies against major histocompatibility complex (MHC)-are among the groups that stand to benefit. There…
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