The American journal of pathologyAnimalsT-LymphocytesRegulatoryNuclear Receptor Subfamily 1Group F
Targeting RORγ to Boost Regulatory T cells and Ameliorate Diabetic Retinopathy in Mice.
Devy Deliyanti, Varaporn Suphapimol, Phoebe Ang, Abhirup Jayasimhan, Jennifer L Wilkinson-Berka
Published: 202610.1016/j.ajpath.2025.09.006
Abstract
Diabetic retinopathy, a leading cause of blindness, features damage to the retinal vasculature, where T-cell-mediated inflammation is increasingly recognized as an important contributor. Retinoic acid receptor-related orphan receptor gamma (RORγ) pla…
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