The American journal of emergency medicineHumansBlood Coagulation FactorsRetrospective StudiesMaleFemale
Evaluating the use of fixed versus variable dosing of 4-factor prothrombin complex concentrate in anticoagulant-related major bleeding.
Elizabeth Schrader, Brianna Zinser, Ashish Kulhari, Cody Craven
Published: 202610.1016/j.ajem.2025.10.019
Abstract
BACKGROUND/OBJECTIVE: 4-factor prothrombin complex concentrate (4F-PCC) is used for reversal of vitamin K antagonists (VKA) and oral factor Xa (FXa) inhibitors in patients with major bleeding, including gastrointestinal bleeding and intracranial hemo…
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