American heart journal
A multicenter trial to test pitavastatin calcium in youth with combined dyslipidemia of obesity: Design, implementation, challenges, and responses.
Sarah D de Ferranti, Jessica E Teng, Silva A Arslanian, Andrew M Atz, Julie A Brothers, Mark J Cartoski, D'Andrea R Freemon, Sheela N Magge, William T Mahle, Michele Mietus-Snyder, Amy Peterson, Geetha Raghuveer, Mark W Russell, Amy S Shah, Craig A Sponseller
Published: 202510.1016/j.ahj.2025.107327
Abstract
BACKGROUND: Combined dyslipidemia of obesity (CDO) is a prevalent atherogenic lipid disorder characterized by high TG, low HDL, high non-HDL, and a preponderance of small LDL particles. Lifestyle modification is the mainstay of treatment but is often…
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