Advanced drug delivery reviews
Covalent chemistry in targeted protein degradation.
Jing Tan, Yuxin Liang, Shiqun Shao, Youqing Shen
Published: 202610.1016/j.addr.2026.115777
Abstract
Targeted protein degradation (TPD) has revolutionized drug discovery by enabling the selective removal of specific proteins within and outside cells through the cell's natural degradation pathways. While various TPD modalities have demonstrated immen…
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