Acta biomaterialia
Local mechanobiological disruption in solid tumor-driven vascular permeability: A competition between mechanical vs chemical stimuli.
Alejandro Martín-Contreras, María Sarasquete-Martínez, José Manuel García-Aznar, Alejandra González-Loyola, María José Gómez-Benito
Published: 202610.1016/j.actbio.2026.01.013
Abstract
The tumor microenvironment imposes complex biochemical and biomechanical constraints on microvasculature, contributing to aberrant tumor blood vessels, characterized by abnormal endothelial proliferation, disrupted cell-to-cell junctions and increase…
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