Acta biomaterialia
Enhancing bioactivity of calcium-phosphate cement-based 3D printed scaffolds with human platelet lysates: in vitro and in vivo validation.
Paula M C Torres, Denise Jahn, Nilza Ribeiro, Tiago R Correia, Miguel Coelho, Tânia S S Carvalho, Agnes Ellinghaus, Ana Prates Soares, Carsten Rendenbach, João F Mano, Katharina Schmidt-Bleek, Susana M Olhero
Published: 202510.1016/j.actbio.2025.12.014
Abstract
The reconstruction of large bone defects remains a significant challenge due to the limited regenerative efficacy of engineered biomaterials compared to autologous grafts. Although ceramic substitutes based on calcium phosphates (CaP) have shown prom…
Preview only. Read the full abstract at the source