Acta biomaterialiaBone RemodelingAnimalsOsteoblastsMiceLab-On-A-Chip Devices
Bone-on-a-chip recapitulates dynamic bone remodeling.
Yujie Zhang, Yuan Zhao, Zhenchong Sun, Chuanfeng An, Guoshuang Zheng, Yi Shen, Xingyu Zhu, Changle Ren, Lijun Zhang, Tao Chen, Yonggang Zhang, Jeroen Jjp van den Beucken, Jianru Xiao, Yang Zhang, Huanan Wang
Published: 202510.1016/j.actbio.2025.10.039
Abstract
Bone remodeling is governed by the basic multicellular unit (BMU) and plays a crucial role in both normal bone function and pathological conditions (e.g. osteoporosis). Unfortunately, our understanding of the bone remodeling process is limited as cur…
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