Acta biomaterialiaExtracorporeal Membrane OxygenationAnimalsAnticoagulantsCoated MaterialsBiocompatible
Silk-based multilayer coatings for anticoagulation and durability improvement in ECMO hollow fiber membranes.
Wenbo Zhang, Yilin Zhang, Chenlu Wang, Xingji Fu, Yuan Li, Hongyu Wang, Xiuyuan Luo, Linhao Li, Yubo Fan, Zengsheng Chen
Published: 202510.1016/j.actbio.2025.10.006
Abstract
In clinical extracorporeal membrane oxygenation (ECMO), prolonged blood residence time in oxygenators can lead to thrombus formation and complications. Heparin-based bioactive coatings are commonly used for anticoagulation, but prolonged shear stress…
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