Acta tropica
Fasciola hepatica excretory and secretory products reprogram the Kupffer cell transcriptome to modulate hepatic damage progression.
Zhuo Lan, Minhao Zeng, Yan Yang, Xue Bai, Xue Wang, Hongyu Qiu, Junfeng Gao, Guofeng Cheng, Santiago Mas-Coma, Chunren Wang
Published: 202610.1016/j.actatropica.2026.107988
Abstract
Fasciola hepatica, a food-borne trematode that parasitizes the liver and bile ducts of cattle, sheep, other ruminants, and humans, is a critical zoonotic disease responsible for substantial hepatic pathology. Kupffer cells (KCs), the resident macroph…
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