Acta tropicaNifurtimoxNitroimidazolesTrypanosoma cruziHumansTrypanocidal Agents
Mechanisms of resistance of Trypanosoma cruzi to benznidazole and nifurtimox: Molecular implications and multifaceted impact.
Paulina Ochoa-Martínez, Jaime López-Domínguez, Aracely López-Monteon, Rebeca Georgina Manning-Cela, Angel Ramos-Ligonio
Published: 202610.1016/j.actatropica.2025.107940
Abstract
Chagas disease, caused by the hemoflagellate protozoan Trypanosoma cruzi, is a parasitic zoonosis classified as a neglected tropical disease. With an estimated global prevalence of 6 to 7 million individuals, the disease represents a significant glob…
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