Acta tropicaAnimalsDisulfiramCryptosporidiosisImmunocompromised HostDrug Therapy
Repurposing disulfiram in a promising combination therapy for cryptosporidiosis in immunocompromised mice.
Amel Youssef Shehab, Engy Mosbah Hassan, Esraa A Moneer, Heba Essam Sedky, Fatma A Abdelkader, Mona Mohamed Tolba, Amal Farahat Allam, Heba Elhadad
Published: 202510.1016/j.actatropica.2025.107929
Abstract
Cryptosporidiosis remains a major health concern, particularly in immunocompromised individuals, due to limited effective treatment options. Nitazoxanide (NTZ) is currently the only FDA-approved drug for cryptosporidiosis, yet its efficacy is signifi…
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