Analytica chimica actaTandem Mass SpectrometryHumansChromatographyHigh Pressure LiquidLiquid-Liquid Extraction
Development of a high-throughput LLE-UPLC-QqQ-MS/MS method and comprehensive profiling of urinary steroid hormones in Chinese elderly adults.
Xiao Ma, Huimin Ren, Li Zhao, Xiaojie Guo, Jiran Zhang, Juan Liu, Xiaona Wang, Mengyao Wang, Yifu Lu, Shilu Tong, Hongyang Cui, Hong Chang, Yu'e Cha, Song Tang, Xiaoming Shi
Published: 202610.1016/j.aca.2025.344994
Abstract
BACKGROUND: Steroid hormones (SHs) in human urine are critical for understanding physiological processes, but their analysis is challenged by intricate urine matrices and diverse SHs physicochemical properties. Existing methods often lack sensitivity…
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