Analytica chimica actaAptamersNucleotideHumansFolate Receptor 1SELEX Aptamer Technique
An integrated microfluidic system equipped with a shear force control device for optimized selection of high-affinity, high-specificity aptamers targeting folate receptor alpha.
Yang-Sheng Shao, Yi-Cheng Tsai, Chih-Hung Wang, To-Wen Chen, Keng-Fu Hsu, Gwo-Bin Lee
Published: 202610.1016/j.aca.2025.344827
Abstract
BACKGROUND: Folate receptor alpha (FRα) is a key biomarker for ovarian cancer diagnosis. Aptamers with high affinity and high specificity targeting FRα were automatically screened herein on an integrated microfluidic system. By automating Systematic…
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