Archives of biochemistry and biophysics
The regulation of CP-31398 on liquid-liquid phase separation of p53.
Yang Liu, Chang Xu, Fangming Jiang, Xiaorong Yang
Published: 202610.1016/j.abb.2026.110735
Abstract
The tumor suppressor p53 could regulate the cell cycle arrest, DNA repair and apoptosis. It underwent liquid-liquid phase separation (LLPS) to form droplets. CP-31398 was thought as the activator of p53. In this work, the regulation of CP-31398 on th…
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